The United States Food and Drug Administration (FDA) has announced that synthetic DMAA (1,3 dimethylamylamine)- the kind found in many popular pre-workout and fat-loss supplements – should not be allowed for sale in sports supplements or other ‘natural’ products. At least ten producers and distributors of these products have received FDA warning letters to cease selling them or risk imminent enforcement.
The reason for this enforcement action is that the FDA has seen scientific evidence that DMAA increases blood pressure and they believe that this effect could cause ‘cardiovascular events’ (heart attacks and strokes). They’ve also received evidence of at least 42 adverse events (negative side effects) in addition to the fact that DMAA was not registered as a ‘New Dietary Ingredient’ (NDI) when it was first made available for sale. Canada has already categorized DMAA as a drug that cannot be used in dietary supplements.
Large US retailers and companies selling DMAA-containing products have correctly stated that there is no proof that DMAA has actually caused these health problems that have included cardiovascular events and even death but it looks like this is the beginning of the decline of DMAA due to questions over its safety, several lawsuits and the enforcement activity being undertaken by FDA.